Ali Fereidouni is a biomedical researcher with a BSc in Medical Laboratory Sciences and an MSc in Medical Biotechnology. His background combines rigorous academic training in molecular and cellular biology with hands-on experience across translational research and pharmaceutical development. He is particularly interested in how molecular signaling systems shape disease biology and how robust laboratory evidence can be translated into real-world diagnostic and therapeutic solutions. Since 2023, Ali has been working at the International Center for Neuroscience Research (ICNR), initially as a Research Assistant in the Neurochemistry of Neurodegenerative Disease research group. His work supports projects that map GPCR signaling, trafficking, and receptor crosstalk to understand how these pathways reshape synaptic plasticity, neuroinflammation, and myelin-related mechanisms in neurodegenerative conditions. A key focus of his research interest is GPCR pharmacology—including positive and negative allosteric modulators and emerging bitopic ligands—with specific emphasis on biased signaling that differentially recruits G-protein versus β-arrestin pathways. In parallel, he contributes to probing metabolism–inflammation links through lipid-mediated neurotransmission and related receptor families, connecting energetic stress and immune tone to neuronal function, plasticity, and circuit resilience.
Ali’s experimental skill set spans a wide range of wet-lab techniques, with strengths in molecular and cellular methods and careful attention to experimental detail, documentation, validation, and analytical interpretation. His recent publication record reflects his contribution to collaborative, internationally oriented research efforts, including participation in projects aligned with European scientific priorities in neurochemistry and neurodegeneration. Currently, Ali serves as Innovation Project Manager at ICNR, where he oversees and accelerates novel neuroscience research programs. In this role, he directs multidisciplinary projects from ideation to delivery, coordinating collaborators, aligning scientific milestones with timelines and funding strategies, and supporting high-impact outcomes that advance innovative and clinically relevant neuroscience. Alongside his academic path, Ali has built strong professional experience in the pharmaceutical industry, including roles in R&D and QA/QC, which have strengthened his expertise in robust workflow design, accuracy/precision thinking, method evaluation and validation, and regulatory-quality documentation. This combination allows him to bridge laboratory science with product-oriented development, bringing a practical mindset shaped by strategic planning, critical thinking, problem-solving, teamwork, leadership, and an innovation-driven approach to translation and commercialization.
Research Interests: Neuropharmacology of GPCRs, Biased signaling, Translational biomarker, Nanopharmaceuticals, Drug discovery
